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* Don Wright Interview by Dr. Sanjay Gupta

KOSIK: And every week, Dr. Sanjay Gupta brings us incredible stories of recovery and survival from around the world. In today’s “Human Factor,” our chief medical correspondent reports on a 71-year-old who’s continued his dream of running marathons while fighting a dangerous form of cancer, one where patients are rarely cured.

http://www.cnn.com/video/#/video/health/2013/01/09/human-factor-don-wright.cnn

SANJAY GUPTA, CNN CHIEF MEDICAL CORRESPONDENT: Don Wright’s career spanned engineering, being a company vice president, and the law. At age 62, he discovered a new passion — marathons. Nine year ago, days after running his first 26-mile race, he got some devastating news.

DON WRIGHT, MARATHON RUNNER/CANCER PATIENT: I had gone to the doctor a couple of times for pain in my back. It was multiple myeloma.

GUPTA: This is a cancer of the blood where the white blood cells invade the bone marrow causing pain, usually in the back or the ribs. Patients are rarely cured. But Wright refused to let that slow him down, even qualifying for the Boston marathon.

WRIGHT: We got this devastating diagnosis, and we just — my family and I, we just kept on going. You know, there wasn’t any reason to stop and be sorry, you know. We kept running marathons.

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WRIGHT: It feels wonderful, I’ll tell you. A philosophy of life that I have is live one day at a time and make it a masterpiece, and that was a masterpiece.

GUPTA: Wright wasn’t sure he could fulfill his dream because the median survival for his cancer is just five years. Prognosis does vary depending on age and stage of the disease. He’s had a number of treatments that have failed. But for the last four-and-a-half years, Wright’s taken an experimental drug, one pill at night, that’s worked. It’s kept the cancer at bay.

WRIGHT: It doesn’t cure the cancer, but it keeps it stable so it’s not hurting me. And I can still run. And I can still enjoy life, and I’m riding that for all it’s worth.

GUPTA: His advice to others facing what seemed like insurmountable odds, take charge of your own destiny and never give up hope.

Dr. Sanjay Gupta, CNN, reporting.

* A Minnesota man who has incurable cancer hits a big milestone

http://www.kvue.com/news/182916671.html

by WCNC

kvue.com

Posted on December 10, 2012 at 8:43 PM
Updated Tuesday, Dec 11 at 7:18 AM

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A Minnesota man who has incurable cancer hits a big milestone.

Seventy-one-year-old Don Wright reached his goal of running marathons in all 50 states. He hit 50 this Sunday in Honolulu.

“My family and I have been running marathons in every state, and that’s been our goal, and we’ve run marathons now in 49 of the 50 states,” Wright said before the race on Sunday, “The diagnosis for my cancer was a three to five-year median survival. It feels like when I’m running along in a marathon, I’m just sticking my finger right in that cancer’s eye.”

Wright has a type of blood cancer.

He says he’s been able to control his battle thanks to a drug that’s being used in clinical trials.

And, he says he’ll keep running as long as he can.

* Cancer survivor runs his 50th marathon in the 50th state

http://www.hawaiinewsnow.com/story/20292980/cancer-survivor-runs-his-50th-marathon-in-the-50th-state

Cancer survivor runs his 50th marathon in the 50th state

Posted: Dec 07, 2012 10:42 PM EST Updated: Dec 08, 2012 1:43 AM EST

By Teri Okita – bio | email

HONOLULU (HawaiiNewsNow) –

Come Sunday morning, organizers are expecting more than 31,000 runners at the Honolulu marathon. In that crowd, a Minnesota man will, appropriately, be running his 50th marathon in the 50th state.

But Hawaii News Now found out: there’s much more to his story.

Don Wright has had plenty of practice crossing the finish line. This Sunday, he’ll have run a 26.2 mile marathon in every state in the nation.

“That’s pretty. I can’t wait ’til I’m running under that!” says Wright – as he looks at the finish line sign that’s not even hung up yet.

At age 71, not many people can say they’ve finished one marathon – let alone 50. It’s pretty impressive for a guy who just picked up running decade ago.

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Age is the least of his challenges. The St. Paul-area man was diagnosed with multiple myeloma – a blood cancer that affects cells in bone marrow. He was given about five years to live – that was nine years ago.

Running became his path to survival.

“It gives me a chance to make a point that people who have cancer can still have active, vital lives,” he says.

When Wright crosses the finish line on Sunday, he figures he will have logged 12,000, maybe 13,000, miles training and running these marathons.

Do the math. That’s like running from one coast to another – Los Angeles to New York – almost five times! His last marathon was just five weeks ago, and in 2011, he ran more than one marathon a month.

“He’s a runner, not a myeloma victim,” says his wife, 73 year old, Ardis. The Wrights and their daughter often race with together.

He’s stabilized on an investigative cancer drug called pomalidomide and needs no infusions or transplants. “We’re free because all he has is that little pill bottle, and he takes one pill every night and we can go,” says Ardis.

And go they do – successfully on the run from cancer.

Copyright 2012 Hawaii News Now. All rights reserved.

* Man with incurable cancer looks to complete quest to run marathons in all 50 states

Man with incurable cancer looks to complete quest to run marathons in all 50 states

Reported by: Olena Heu

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Click here to read the full article and see the video

One of the participants in Sunday’s Honolulu Marathon has overcome many obstacles to get here. The Minnesota resident was diagnosed with an incurable cancer.

Don Wright, 71, says he loves to run.

“I feel like I am floating past the scenery and just gliding along watching it go by,” Wright said.

Nearly 10 years ago, just days after Don’s first marathon, he was diagnosed with myeloma, which is a cancer of the blood.

“The diagnosis for my cancer was a three-to-five year median survival,” Wright said.

Inspired not to let the disease keep him down, the Minnesota resident decided to keep running.

“My family and I have been running marathons in every state. That’s been our goal and now we’ve run marathons in 49 of the 50 states,” Wright said.

When he completes the Honolulu Marathon on Sunday Don will achieve his goal of running 50 marathons in all 50 states…in the 50th state.

“It feels like when I am running along in a marathon like I have just stuck my finger right in that cancer’s eye,” Wright said.

Don runs with the hope of raising funds and awareness for The Tackle Cancer Foundation and has been able to control his battle with cancer thanks to a drug currently being used in clinical trials for his condition.

“That has kept it stable for five years and I actually feel very good,” Wright said.

Will this be his last marathon?

“This will never, no, no I will keep running marathons until I can’t, and that’s hopefully a long way off,” Wright said.

Click HERE to view Wright’s running blog.

* 50-state marathon runner stops in N.M.

50-state marathon runner stops in N.M.

http://www.koat.com/news/new-mexico/albuquerque/Marathon-Man/-/9153728/17072524/-/4xbrdv/-/index.html

Despite incurable cancer, man runs in dozens of marathons
Published 10:02 AM MDT Oct 21, 2012
ALBUQUERQUE, N.M. –
A Minnesota man diagnosed with an incurable form of cancer is on the run of his life as tries to run 50 marathons in 50 states.

Action 7 News reporter Tanya Mendis spoke with Don Wright on Sunday about his drive to keep running no matter what.

Wright said he was diagnosed with myeloma at 62. Nine years later, the 71-year-old has run marathons in 48 states.

Wright said he hopes to make New Mexico his 49th state.

“When I run, to be honest, I feel like I’m poking that cancer right in the eye,” Wright said.

So far he has run 69 marathons in 48 states.
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“I’d like people to be healthy and think healthy and if I’m an inspiration, that’s all the better,” Wright said.

He said he wouldn’t been able to run more than a few miles, if not for a special trial cancer drug he began four years ago.

“Which for me has turned out to be a miracle drug. It keeps the cancer stable, it doesn’t cure the cancer but it keeps it at a level where the cancer doesn’t hurt me,” Wright said.

He said he might not ever fully escape his cancer but he’s giving it the race of his life.

“The cancer numbers went down to about one-third of what they were to where it’s safe,” Wright said.

Wright did admit that he’s a little old to be running five or six days a week but he doesn’t plan to stop running marathons.

Wright will take part in the Duke City Marathon on Monday.
He said he plans on running his 50th and final state in Hawaii in December.

After that, he might try Canada.

* New antidepressant studied here



http://abclocal.go.com/wpvi/story?section=news/health&id=8545273

ROOMALL, PA.; February 15, 2012 (WPVI) — There is new hope for people who suffer from depression. Final trials are underway on a new antidepressant.

Dr. Ronald Fuchs of Sproul Medical Center in Broomall, says it’s a common story. A patient on antidepressants needing higher and higher doses to get any relief, only to develop side effects that drive the sufferer to stop taking the medication altogether.

He’s taking part in the TRIADE trial, phase 3 tests of a new type of antidepressant.

Amitifadine is intended for people who failed with other medications.

It elevates levels of 3 chemicals in the brain – serotonin, dopamine, and norepinephrine. Other antidepressants only act on one or two of those.
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Dr. Ronald Fuchs, of Sproul Medical Center in Broomall, says, “By working on 3 different pathways, at different percentages of these mechanisms, the potential for remission of symptoms – or control of symptoms – is higher because you’re not just coming at it from one direction.”

Dr. Fuchs, who is one of the local doctors involved in the study, says the three-pronged approach may also reduce the side effects of other antidepressants

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To find out more about the study, call 610-356-0662, or see TRIADE trial.

(Copyright ©2012 WPVI-TV/DT. All Rights Reserved.)

 

* Human Factor: Running marathons while fighting cancer at 70

Click on the link below to view the video
http://www.cnn.com/video/#/video/health/2011/11/29/hf-don-wright-marathon.cnn
November 29, 2011

Human Factor: Running marathons while fighting cancer at 70

In the Human Factor, we profile survivors who have overcome the odds. Confronting a life obstacle – injury, illness or other hardship –- they tapped their inner strength and found resilience they didn’t know they possessed. This week we meet Don Wright, who developed a passion for running marathons later in life, right before getting diagnosed with cancer. His goal is to run 50 marathons in 50 states.

“I’ve made an appointment with an oncologist for you.” These are words that no one wants to hear from their doctor, ever. It was multiple myeloma, an incurable blood cancer with a median survival of about five years after diagnosis.

I had lost weight at Weight Watchers’, then started running, and had just run my first marathon. Myeloma attacks the bones, and a broken bone would stop my running, so I was determined to run the Boston Marathon before I lost the ability to do so. I qualified for Boston and then ran it, then a few more marathons here and there. I had no reasonable expectation of finishing all 50 states.

That was eight years ago. I’m now 70 years old and since the diagnosis I have run 60 marathons in 41 different states, including the Seattle Marathon last Sunday. After some treatments that didn’t stop it, the cancer has been stable for three and a half years on a novel investigational drug called pomalidomide, just a pill that I take once a day. I’m a beneficiary of modern innovation and research.

I have this incurable cancer, and my most pressing health problem is runners’ knee!
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My doctors are uniformly enthusiastic about the running as a way to strengthen my immune system and my bones. “We’re not sure why it works, but keep doing what you’re doing.”

We can’t know how long this treatment will continue to keep the cancer from growing, but for now, my family and I are relishing the extra time that I have been given, by traveling and doing these marathons together. They are a celebration of life!

I stand at the starting line and get choked up, thinking of the people I know who haven’t survived myeloma, and how lucky I am to be alive and able to run a marathon. I can’t wait to start the race. Even on a cold, rainy day in Seattle, I enjoyed every moment. As I run, I sometimes imagine that I’m just floating along, drifting past the scenery. I feel wonderful, and we’re going for all 50 states.

Since August I have also been running on behalf of Team Continuum, a charity started by a man with myeloma. It helps patients and their families meet their daily expenses while fighting cancer. Here’s how you can help:

– Click “like” on this Facebook page and a donor will contribute $5.00 at no cost to you: facebook.com/ERACECANCER.

– Go here if you would like to make your own donation directly to
TeamContinuum.net.

With my cancer I am very lucky to be able to run marathons, and I feel even more privileged to run them on behalf of other cancer patients.

* Cancer patient runs marathons

Cancer patient runs marathons

Sanjay Gupta MD|Added on November 28, 2011

Dr. Sanjay Gupta talks to a cancer patient whose goal is to run a marathon in every state.
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